Capturing a crucial 'disorder-to-order transition' at the heart of the coronavirus molecular pathology - triggered by highly persistent, interchangeable salt-bridges
S. Roy, P. Ghosh, A. Bandyapadhyay, S. Basu
The paper investigates the disorder-to-order transition in the SARS-CoV-2 Spike protein upon Furin binding, highlighting salt-bridge networks and their role in proteolytic cleavage efficiency.
bioRxiv · Dec 29, 2021Biophysics