Author

A. Basciu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1 Approach:simulation· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

A. V. Vargiu· 2 shared G. Malloci· 2 shared A. Bonvin· 1 shared A. Bosin· 1 shared A. M. J. J. Bonvin· 1 shared C. Neville· 1 shared F. Muredda· 1 shared F. Pietrucci· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

A. V. Vargiu

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2 papers

Recent·Most cited

Predicting binding events in very flexible, allosteric, multi-domain proteins

A. Basciu, M. Athar, H. Kurt, C. Neville, G. Malloci, F. Muredda, A. Bosin, P. Ruggerone, A. Bonvin, A. V. Vargiu

This paper introduces a method to generate bound-like conformations of flexible, multi-domain proteins using unbound structures and binding site information, demonstrating its effectiveness on adenylate kinase.

bioRxiv · Jun 2, 2024Biophysics

An enhanced-sampling MD-based protocol for molecular docking

A. Basciu, G. Malloci, F. Pietrucci, A. M. J. J. Bonvin, A. V. Vargiu

This paper introduces an enhanced-sampling MD-based protocol to generate druggable protein conformations using metadynamics, improving docking accuracy for drug design.

bioRxiv · Oct 3, 2018Biophysics