Rapid Molecular Mechanotyping with Microfluidic Force Spectroscopy
M. van Galen, A. Bok, T. Peshkovsky, J. van der Gucht, B. Albada, J. Sprakel
This paper introduces microfluidic force spectroscopy (microFFS) as a rapid, low-cost method to measure molecular bond stability under mechanical forces, validated with DNA duplexes and simulations.
bioRxiv · Feb 17, 2023 · PreprintBiophysics