Loop statistics and fountain geometry reveal effective two-sided cohesin extrusion and crowding-induced arm desynchronization
A. Chervinskaya, Mikhail Sergeevich Gelfand, Ralf Metzler, Kirill Polovnikov
The paper develops a kinetic theory of cohesin extrusion to explain loop statistics and fountain geometry, finding that cohesin crowding and roadblock dynamics determine loop lengths and arm coordination.
bioRxiv · Aug 20, 2026 · PreprintBiophysics