Cancer BiologybioRxiv
Alternative Lengthening of Telomeres is not synonymous with mutations in ATRX/DAXX
A. de Nonneville, R. R. Reddel
The paper reanalyzes PCAWG data to show that ATRX/DAXX mutations are not reliable indicators of ALT and proposes a new classifier based on C-circle assays.
DOI 10.1038/s41467-021-21794-0