Allostery in Proteins as Point-to-Point Telecommunication in a Network: Frequency Decomposed Signal-to-Noise Ratio and Channel Capacity Analysis
Y. Bozkurt Varolgunes, J. F. Rudzinski, A. Demir
The paper introduces a frequency-domain framework to analyze allostery in proteins by modeling ligand-induced displacements and noise fluctuations, using signal-to-noise ratio and channel capacity analysis to identify new allosteric regions.
bioRxiv · Feb 26, 2021 · PreprintBiophysics