Author

A. E. Panaitiu

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Bioengineering· 1

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1

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G. Grigoryan· 1 shared J. Zhou· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperBioengineering

G. Grigoryan

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1 paper

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BioengineeringbioRxivOct 1, 2018

A general-purpose protein design framework based on mining sequence-structure relationships in known protein structures

J. Zhou, A. E. Panaitiu, G. Grigoryan

This paper introduces a protein design framework called dTERMen that uses sequence-structure compatibility patterns from known proteins to generate functional sequences, showing it can produce stable, foldable proteins with desired structures.

DOI 10.1073/pnas.1908723117

protein sequenceprotein structure

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