Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules
S. Nersisyan, A. Zhiyanov, M. Zakharova, I. Ishina, I. Kurbatskaia, A. Mamedov, A. Galatenko, M. Shkurnikov, A. Gabibov, A. Tonevitsky
The paper analyzes how SARS-CoV-2 Omicron and Delta variants affect peptide presentation by HLA molecules, finding reduced binding for specific Spike peptides but overall maintained T-cell immunity.
bioRxiv · Feb 21, 2022 · PreprintImmunology