Evolutionary Adaptation of Prephenate Dehydrogenases: A regulatory ACT domain acquisition in ecological niche specialization
A. Gritsunov, I.G. Shabalin, Jing Hou, W. Minor, D. Christendat
This study investigates the role of the ACT domain in prephenate dehydrogenase (PDH) allosteric regulation and its evolutionary significance in bacterial metabolic adaptation.
bioRxiv · Oct 30, 2025 · PreprintBiochemistry