Author

A. H. B. Frederiksen

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Biophysics· 1

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Assay:protein sequence· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

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A. Stein· 1 shared K. Lindorff-Larsen· 1 shared M. Cagiada· 1 shared M. H. Hoie· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperBiophysics

A. Stein

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1 paper

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BiophysicsbioRxivJun 26, 2021

Predicting and interpreting large scale mutagenesis data using analyses of protein stability and conservation

M. H. Hoie, M. Cagiada, A. H. B. Frederiksen…·K. Lindorff-Larsen

The paper predicts and interprets large-scale mutagenesis data by analyzing protein stability and conservation, finding that sequence conservation provides more accurate variant effect predictions than stability calculations.

DOI 10.1016/j.celrep.2021.110207

protein sequencestatistical model

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