Gold-standard diagnostics are tarnished by lytic bacteriophage
E. J. Nelson, J. A. Grembi, D. L. Chao, J. R. Andrews, L. Alexandrova, P. H. Rodriguez, V. V. Ramachandran, M. A. Sayeed, J. Wamala, A. K. Debes, D. A. Sack, A. J. Hryckowian, F. Haque, S. Khatun, M. M. Rahman, , G. K. Schoolnik
This study shows that lytic bacteriophage and antibiotic exposure reduce diagnostic positivity for cholera, suggesting that current diagnostic methods may underestimate cholera burden.
bioRxiv · Jan 30, 2020 · PreprintMicrobiology