Interaction of lecithin-cholesterol acyltransferase with lipid surfaces and apolipoprotein A-I derived peptides: implications for the cofactor mechanism of apolipoprotein A-I
M. G. Casteleijn, P. Parkkila, T. Viitala, A. Koivuniemi
This study investigates how LCAT interacts with lipid surfaces and apoA-I peptides to catalyze cholesterol esterification, revealing mechanistic insights into its cofactor mechanism and potential for CHD prevention.
bioRxiv · Dec 15, 2017Biophysics