BIRC3: A Prognostic Predictor and Novel Therapeutic Target in TMZ-Resistant Glioblastoma Tumors
M. Morelli, S. Franceschi, F. Lessi, P. Aretini, A. Pastore, E. Corradi, A. Marranci, C. Gambacciani, F. Pieri, G. Grimod, N. Montemurro, M. Giacomarra, M. Menicagli, G. Ferri, F. Pasqualetti, , C. M. Mazzanti
This study identifies BIRC3 as a prognostic biomarker and therapeutic target for TMZ-resistant glioblastoma, validated across multiple datasets and showing efficacy when combined with AZD5582.
bioRxiv · Aug 23, 2023 · PreprintCancer Biology