Author

C. M. Mazzanti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

C. Gambacciani· 2 shared F. Lessi· 2 shared F. Pasqualetti· 2 shared F. Pieri· 2 shared M. Menicagli· 2 shared M. Morelli· 2 shared P. Aretini· 2 shared S. Franceschi· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

C. Gambacciani

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Author profile →

3 papers

Recent·Most cited

BIRC3: A Prognostic Predictor and Novel Therapeutic Target in TMZ-Resistant Glioblastoma Tumors

M. Morelli, S. Franceschi, F. Lessi, P. Aretini, A. Pastore, E. Corradi, A. Marranci, C. Gambacciani, F. Pieri, G. Grimod, N. Montemurro, M. Giacomarra, M. Menicagli, G. Ferri, F. Pasqualetti, , C. M. Mazzanti

This study identifies BIRC3 as a prognostic biomarker and therapeutic target for TMZ-resistant glioblastoma, validated across multiple datasets and showing efficacy when combined with AZD5582.

bioRxiv · Aug 23, 2023 · PreprintCancer Biology

Single-cell molecular characterization to partition the human glioblastoma tumor microenvironment (TME) genetic background

F. Lessi, S. Franceschi, M. Morelli, M. Menicagli, F. Pasqualetti, O. Santonocito, C. Gambacciani, F. Pieri, F. Aquila, P. Aretini, C. M. Mazzanti

This study uses single-cell techniques to analyze genetic mutations in different cell types of glioblastoma tumors, revealing new insights into tumor heterogeneity and genetic background.

bioRxiv · Feb 10, 2022Cancer Biology

Differential roles of pyramidal and fast-spiking, GABAergic neurons in the control of glioma cell proliferation

E. Tantillo, E. Vannini, C. Cerri, C. Spalletti, A. Colistra, C. M. Mazzanti, M. Costa, M. Caleo

This study shows that optogenetic stimulation of pyramidal neurons increases glioma proliferation, while stimulation of fast-spiking GABAergic neurons decreases it, with sensory input effects being region-specific.

bioRxiv · Mar 5, 2020Cancer Biology