Skeletal muscle tissue secretes more extracellular vesicles than white adipose tissue and myofibers are a major source ex vivo but not in vivo.
A. L. Estrada, Z. Valenti, G. Hehn, C. Allen, N. Kruh-Garcia, D. Lark
The paper compares EV secretion between skeletal muscle and white adipose tissue, finding SkM secretes more EVs ex vivo, but myofiber-derived EVs rarely enter circulation in vivo.
bioRxiv · Sep 27, 2020 · PreprintPhysiology