Single-Cell RNA-seq based elucidation of the antidepressant hyperforin biosynthesis de novo in St. John's wort.
S. Wu, A. L. M. Morotti, J. Yang, E. Wang, E. C. Tatsis
The paper identifies Hyper cells in St. John's wort where hyperforin biosynthesis occurs de novo and characterizes four prenyltransferases involved in its synthesis.
bioRxiv · Jan 24, 2024Plant Biology