A novel transplantable model of lung cancer associated tissue loss and disrupted muscle regeneration
P. C. Arneson, A. M. Ducharme, J. D. Doles
This study develops a new lung cancer-associated cachexia model that improves upon existing models by using tail vein injection, longer survival times, and older mice, showing progressive weight loss and muscle wasting with implications for muscle regeneration.
bioRxiv · Feb 4, 2020Cancer Biology