Exploring the Chain Release Mechanism from an Atypical Apicomplexan Polyketide Synthase
A. M. Keeler, P. E. Petruzziello, E. G. Boger, H. K. D'Ambrosio, E. R. Derbyshire
This study characterizes the thioester reductase domain of TgPKS2 from Toxoplasma gondii, revealing its unique chain release mechanism and upregulation in cyst-forming bradyzoites.
bioRxiv · May 23, 2023 · PreprintBiochemistry