The EphB2-MYC Axis is a Major Determinant of Barrett's Pathobiology and a Therapeutic Vulnerability in Esophageal Cancer
S. Venkitachalam, D. Babu, D. Ravillah, R. M. Katabathula, P. Joseph, S. Singh, B. Udhayakumar, Y. Miao, O. Martinez-Uribe, J. A. Hogue, A. M. Kresak, D. Dawson, T. LaFramboise, J. E. Willis, A. Chak, , K. Guda
This study identifies the EphB2-MYC axis as a key driver of Barrett's Esophagus progression to esophageal adenocarcinoma and a potential therapeutic target.
bioRxiv · May 13, 2021 · PreprintCancer Biology