A Slow but Steady NanoLuc: R162A mutation results in a decreased, but stable, NanoLuc activity
W. S. Ahmed, A. M. Geethakumari, A. Sultana, A. Fatima, A. M. Philip, S. M. Nasiruddin, K. H. Biswas
This study shows that the R162A mutation reduces but stabilizes NanoLuc activity, identified through molecular dynamics simulations and mutational analysis.
bioRxiv · Mar 5, 2023Biophysics