Cotranscriptional RNA strand exchange underlies the gene regulation mechanism in a purine-sensing transcriptional riboswitch
L. Cheng, E. N. White, N. L. Brandt, A. M. Yu, A. A. Chen, J. B. Lucks
The paper investigates how ligand binding induces conformational changes in a purine-sensing riboswitch by stabilizing intermediate structures through strand exchange processes.
bioRxiv · Oct 25, 2021Biochemistry