Evolutionary BiologybioRxiv
Oncogenes, tumor suppressor and differentiation genes represent the oldest human gene classes and evolve concurrently
A. Makashov, S. V. Malov, A. P. Kozlov
The paper investigates the evolutionary ages of human gene classes, finding that oncogenes, tumor suppressor genes, and differentiation genes are among the oldest and evolve together.
DOI 10.1038/s41598-019-52835-w