Proteomic profiling of mitochondrial-derived vesicles in brain reveals enrichment of respiratory complex sub-assemblies and small TIM chaperones
R. F. Roberts, A. N. Bayne, T. Goiran, D. Levesque, F. M. Boisvert, J.-F. Trempe, E. A. Fon
The paper identifies proteins enriched in brain mitochondrial-derived vesicles (MDVs), revealing OXPHOS proteins and small TIM chaperones, and shows no significant difference in MDV proteomes between wild-type and PINK1-/- or Parkin-/- mice.
bioRxiv · Jul 6, 2020Biochemistry