Author

A. O. Stevens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:protein structure· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Y. He· 2 shared J. Berendzen· 1 shared J. L. Binder· 1 shared J. Wang· 1 shared N. V. Dokholyan· 1 shared T. I. Oprea· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersPharmacology & Toxicology

Y. He

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2 papers

Recent·Most cited

AlphaFold Models Illuminate Half of Dark Human Proteins

J. L. Binder, J. Berendzen, A. O. Stevens, Y. He, J. Wang, N. V. Dokholyan, T. I. Oprea

The paper uses AlphaFold models to predict protein structures for understudied human proteins, finding that 95% of models with confidence scores above 80 are accurate at the fold level.

bioRxiv · Nov 4, 2021 · PreprintPharmacology & Toxicology

The electrostatic allostery could be the trigger for the changes in dynamics for the PDZ domain of PICK1

A. O. Stevens, Y. He

This study uses molecular dynamics simulations to show that ligand binding to the PICK1 PDZ domain induces electrostatic allostery, altering its dynamics and potentially affecting PICK1 function.

bioRxiv · Oct 6, 2020 · PreprintBiochemistry