Ligand Modulation of the Conformational Dynamics of the A2A Adenosine Receptor Revealed by Single-Molecule Fluorescence
D. D. Fernandes, C. Neale, G.-N. W. Gomes, Y. Li, A. Malik, A. Pandey, A. Orazietti, X. Wang, L. Ye, S. Prosser, C. C. Gradinaru
This study uses single-molecule fluorescence to analyze how ligands modulate conformational dynamics of the A2A adenosine receptor, revealing ligand-dependent changes in state transitions and dynamics.
bioRxiv · Sep 20, 2020Biophysics