Interhelical E@g-N@a Interactions Modulate Coiled Coil Stability within a De Novo Set of Orthogonal Peptide Heterodimers
A. R. Perez, Y. Lee, M. E. Colvin, A. D. Merg
This study designs orthogonal coiled coil peptides and shows that interhelical E@g-N@a interactions enhance thermal stability through hydrogen bonding networks.
bioRxiv · May 23, 2023Biochemistry