Detection of M-Protein in Acetonitrile Precipitates of Serum using MALDI-TOF Mass Spectrometry
N. Mehra, G. Gopisetty, J. Subramani, A. Rajamanickam, S. Sundersingh, P. Karunakaran, J. Perumal Kalaiyarasi, K. Kannan, V. Radhakrishnan, S. Tenali Gnana, R. Thangarajan
This study demonstrates an alternative MALDI-TOF MS method for detecting M-protein in serum using acetonitrile precipitation and immunoenrichment, achieving over 90% concordance with standard methods.
bioRxiv · Mar 13, 2020 · PreprintBiochemistry