Author

A. Rozhok

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:mouse· 1

Frequent Co-Authors

J. DeGregori· 3 shared A. Amon· 1 shared R. E. Silberman· 1 shared

Activity by Year

2018-2018 · peak 3/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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3 shared papersCell Biology

J. DeGregori

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3 papers

Recent·Most cited

A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution

A. Rozhok, R. E. Silberman, A. Amon, J. DeGregori

This paper uses Monte Carlo modeling to show that aneuploid cell frequency peaks after bone marrow transplantation due to reduced purifying selection from population expansion and radiation-induced niche damage.

bioRxiv · Jun 26, 2018Cell Biology

Somatic maintenance impacts the evolution of mutation rate

A. Rozhok, J. DeGregori

This study shows that somatic maintenance and longevity influence mutation rate evolution by modulating the cost of somatic mutations through stochastic modeling.

bioRxiv · Jun 25, 2018Evolutionary Biology

A generalized theory of somatic evolution

A. Rozhok, J. DeGregori

This study uses Monte Carlo modeling to show that the Multi-Stage Model of Carcinogenesis needs modification to explain cancer incidence and stem cell clonality.

bioRxiv · Apr 9, 2018Cancer Biology