A. S. Moffett

Comparing kinetic proofreading and kinetic segregation for T cell receptor activation

This paper compares kinetic proofreading and kinetic segregation models for T cell receptor activation, finding that experimental evidence supports the kinetic segregation model in certain parameter regions.

Modeling the role of immune cell conversion in the tumor-immune microenviroment

The paper develops an ecological model of the tumor-immune microenvironment to study immune cell conversion and its impact on tumor-immune coexistence.

Destructive and constructive cheater suppression through quorum sensing

This study shows quorum sensing can either harm or benefit bacterial populations depending on public good production costs and cheater presence.

Molecular Mechanism of Brassinosteroids Perception by the Plant Growth Receptor BRI1

This study investigates the molecular mechanisms of brassinosteroid binding to the BRI1 receptor using molecular dynamics simulations, revealing differences in binding affinity and conformational changes between two bioactive BRs.

How do brassinosteroids activate their receptors?

This study investigates how brassinosteroids (BRs) activate their receptors BRI1 and BAK1 in Arabidopsis thaliana using molecular dynamics simulations, revealing key contributions of BR interactions and conformational changes to receptor association.