Author

A. S. Petrov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:comparative / phylogenetic analysis· 3 Approach:statistical model· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:phylogenetics / evolution· 2 Assay:protein sequence· 2

Frequent Co-Authors

L. D. Williams· 6 shared C. Alvarez-Carreno· 3 shared J. B. Glass· 2 shared P. I. Penev· 2 shared A. Hernandez-Gonzalez· 1 shared A. R. Reddi· 1 shared A. T. Huynh· 1 shared A. Torres-Larios· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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6 shared papersEvolutionary Biology

L. D. Williams

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6 papers

Recent·Most cited

BEAN and HABAS: Polyphyletic insertions in RNAP that point to deep-time evolutionary divergence of bacteria

C. Alvarez-Carreno, A. T. Huynh, A. S. Petrov, C. Orengo, L. D. Williams

The paper identifies BEAN and HABAS domains in bacterial RNA polymerase subunits, showing their evolutionary divergence and phylogenetic distribution.

bioRxiv · Apr 2, 2024 · PreprintEvolutionary Biology

Common evolutionary origins of the bacterial glycyl tRNA synthetase and alanyl tRNA synthetase

C. Alvarez-Carreno, M. Arciniega, L. Ribas de Pouplana, A. S. Petrov, A. Hernandez-Gonzalez, M. I. Valencia-Sanchez, L. D. Williams, A. Torres-Larios

The paper investigates the evolutionary origins of bacterial glycyl tRNA synthetase (bacGlyRS) and its relationship to alanyl tRNA synthetase, finding common ancestral domains and suggesting a stepwise domain accumulation process.

bioRxiv · May 29, 2023Evolutionary Biology

The Evolution of Protein Folds by Creative Destruction

C. Alvarez-Carreno, R. J. Gupta, A. S. Petrov, L. D. Williams

The paper identifies a mechanism called creative destruction that explains how new protein folds evolve from existing ones through gene duplication, merging, and adaptation.

bioRxiv · Mar 30, 2022 · PreprintEvolutionary Biology

Supersized ribosomal RNA expansion segments in Asgard archaea

P. I. Penev, S. Fakhretaha-Aval, V. J. Patel, J. J. Cannone, R. R. Gutell, A. S. Petrov, L. D. Williams, J. B. Glass

The paper identifies supersized rRNA expansion segments in Asgard archaea, suggesting they may represent an intermediate step in the evolution of eukaryotic ribosomal complexity.

bioRxiv · Dec 25, 2019Evolutionary Biology

G-quadruplex formation on specific surface-exposed regions of the human ribosomal RNA

S. Mestre-Fos, P. I. Penev, S. Suttapitugsakul, C. Ito, A. S. Petrov, R. M. Wartell, R. Wu, L. D. Williams

This study identifies G-quadruplex-forming regions in human ribosomal RNA, specifically in Expansion Segment 7, and shows their presence in chordate LSU rRNA.

bioRxiv · Nov 16, 2018Biochemistry

Multiple prebiotic metals mediate translation

M. S. Bray, T. K. Lenz, J. W. Haynes, J. C. Bowman, A. S. Petrov, A. R. Reddi, N. V. Hud, L. D. Williams, J. B. Glass

The paper tests whether Fe2+ and Mn2+ could replace Mg2+ in ribosome function under ancient Earth conditions, finding they can mediate translation and associate with the ribosome.

bioRxiv · Oct 4, 2018Biochemistry