Distinct Quaternary States, Intermediates, and Autoinhibition During Loading of the DnaB-Replicative Helicase by the Phage {lambda}P Helicase Loader
A. Shatarupa, D. Brown, P. D. Olinares, J. D. Chase, E. Isiorho, B. Chait, D. Jeruzalmi
This study identifies two distinct quaternary states of the DnaB-λP loader complex during DNA replication initiation, revealing structural changes and autoinhibition mechanisms.
bioRxiv · Dec 30, 2022Biochemistry