An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice (Acomys)
A. Tomasso, K. Bartscherer, A. W. Seifert
This study identifies ERK signaling as a key regulator of tissue regeneration versus fibrosis in spiny mice, showing that sustained ERK activity promotes regeneration while its inhibition leads to fibrosis.
bioRxiv · Jun 27, 2022Cell Biology