NMR structure of the Orf63 pro-lytic protein from lambda bacteriophage
N. Khan, T. Graham, K. Franciszkiewicz, S. Bloch, B. Nejman-Falenczyk, A. Wegrzyn, L. W. Donaldson
The paper determines the NMR structure of Orf63 from lambda bacteriophage and uses machine learning to design a ligand targeting its hydrophobic cleft, suggesting potential therapeutics for EHEC outbreaks.
bioRxiv · Oct 3, 2023 · PreprintBiochemistry