Alteration in the intracellular Na+/K+ ratio regulates gene expression through the shift of G-quadruplex dynamics in living cells
Dmitrii A. Fedorov, A.M. Gorbunov, Eugene G. Maksimov, Svetlana V. Sidorenko, Anna M. Varizhuk, Andrey V. Aralov, O.E. Kvitko, Irina Yu. Petrushanko, Alexander А. Makarov, O. D. Lopina, Е. А. Климанова
The paper shows that changes in intracellular Na+/K+ ratio affect gene expression by altering G-quadruplex dynamics in HeLa cells.
bioRxiv · Oct 30, 2025 · PreprintBiochemistry