De Novo Design and AlphaFold3 Evaluation of Protein Binders Targeting Specific Sites of MAP4K4
Aarnav Jain, Alexander V. Tobias
The paper designs small protein binders targeting specific MAP4K4 sites using computational tools and evaluates their binding using AlphaFold3, finding high-confidence candidates with novel sequence space solutions.
bioRxiv · Sep 7, 2026 · PreprintBioengineering