Author

Alexander V. Tobias

ORCID 0000-0002-5866-5254Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein design· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Organism:human· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Aarnav Jain· 1 shared Emily R Sragovicz· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

2 top collaborators · 0 mutual co-author links

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1 shared paperBioengineering

Aarnav Jain

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintOct 27, 2026

Computational Design and Evaluation of De Novo Protein Minibinders Targeting Specific Sites of STAT3

Emily R Sragovicz, Alexander V. Tobias

The paper designs and evaluates de novo protein minibinders targeting specific STAT3 sites using AI and AlphaFold3, identifying high-confidence binders with novel sequences.

DOI 10.64898/2026.10.24.761574

protein sequencedeep learning

𝕏 PostBluesky

BioengineeringbioRxivPreprintSep 7, 2026

De Novo Design and AlphaFold3 Evaluation of Protein Binders Targeting Specific Sites of MAP4K4

Aarnav Jain, Alexander V. Tobias

The paper designs small protein binders targeting specific MAP4K4 sites using computational tools and evaluates their binding using AlphaFold3, finding high-confidence candidates with novel sequence space solutions.

DOI 10.64898/2026.09.04.749196

humanprotein structure

𝕏 PostBluesky