Protective role of Cannabidiol against nicotine pouch-induced seizure aggravation and alterations in brain glymphatic biomarkers.
Bidhan Bhandari, Sahar Emami Naeini, Hannah Mallalieu Rogers, Abdullah Hassan Alhashim, Jack Chung-Kai Yu, Mohammad Seyyedi, Nancy Young, Ahmed A. Elmarakby, Évila Lopes Salles, Lei P. Wang, Babak Baban
This study shows that chronic nicotine pouch exposure worsens seizures and glymphatic function in mice, but inhaled CBD reverses these effects.
Nicotine & Tobacco Research · Dec 11, 2025Peer-reviewedNeuroscience