Loss of CFIm activates YAP/TAZ and connects mRNA cleavage and polyadenylation inhibition to BRCAness
Madeleine Goldthorpe, Jiahui Hou, Abhi Nadendla, Hatice U. Osmanbeyoglu, Hun‐Way Hwang
The paper shows that loss of CFIm activates YAP/TAZ and links mRNA cleavage and polyadenylation inhibition to BRCAness through DNA repair gene repression.
bioRxiv · Oct 21, 2025 · PreprintMolecular Biology