Cell BiologybioRxivPreprint
cAMP Signaling Regulates DNA Demethylation by Augmenting the Intracellular Labile Ferrous Iron Pool
Vladimir Camarena, David W. Sant, Tyler C. Huff…·Gaofeng Wang
This study shows cAMP signaling increases intracellular labile Fe(II) to promote 5hmC formation and DNA demethylation, linking GPCR activation to gene transcription regulation.
DOI 10.1101/162743