The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology
Jonathan L. Chen, Walter N. Moss, Adam Spencer, Peiyuan Zhang, Jessica L. Childs‐Disney, Matthew David Disney
The paper identifies structured regions in tau pre-mRNA that influence splicing and stability, potentially offering new therapeutic targets for tauopathies.
PLoS ONE · Jul 10, 2019Peer-reviewedBioinformatics