Walter N. Moss

ScanFold3 improves RNA structure prediction speed and accuracy, outperforming previous versions in benchmarking and validation.

The paper develops a live-cell method to identify RNA-small molecule interactions and uses it to design selective RNA degraders.

The paper identifies a conserved RNA structure in the TNFRSF1A 3'UTR that may regulate TNFR1 translation and interacts with HuR.

The paper analyzes RSV RNA structures and finds conserved motifs that may impact viral replication, using bioinformatics and experimental methods.

The paper identifies a set of endogenous retroviruses (ERVs) whose expression predicts survival in multiple cancers and is linked to immune response signatures.

This study determines the secondary structure of SARS-CoV-2 subgenomic RNA M through in vitro probing, revealing features important for its function and potential therapeutic applications.

This paper analyzes RNA structure in key genes of Mycobacterium ulcerans to identify conserved structural motifs and regions that may be targeted for therapeutic intervention.

This paper uses ScanFold to map the RNA structural landscape of SARS-CoV-2 and identifies potential drug targets and antisense therapeutic regions.

The paper identifies structured regions in tau pre-mRNA that influence splicing and stability, potentially offering new therapeutic targets for tauopathies.

The paper identifies stable secondary structures in MYC mRNA, including a conserved 3′ UTR motif that affects gene expression and offers potential druggable targets.

The paper identifies human regulatory proteins interacting with a structured intronic region of the LMP2 pre-mRNA and shows actin's role in splicing regulation.