Myeloid STING restrains cardiac remodeling by suppressing macrophage amyloid precursor protein
Niranjana Natarajan, Ebin Johny, Varsha Sriram, Mika Hara, Praise Ama Antwi, Lee Ohayon-Steckel, Aarush Dutta, Adarsh Raj, Partha Dutta
This study shows myeloid STING suppresses cardiac remodeling after myocardial infarction by inhibiting APP expression through the STING-MZF1-APP axis.
bioRxiv · Jul 3, 2026 · PreprintCell Biology