β2-Arrestin germline knockout does not attenuate opioid respiratory depression
Iris Bachmutsky, Xin Paul Wei, Adelae Durand, Kevin Yackle
This paper shows that β2-Arrestin germline knockout does not reduce opioid-induced respiratory depression in mice, challenging the biased agonist hypothesis.
eLife · May 18, 2021Peer-reviewedNeuroscience