MTORC2 is a physiological hydrophobic motif kinase of S6 Kinase 1.
Sheikh Tahir Majeed, Rabiya Majeed, Aijaz A. Malik, Muhammad Afzal Zargar, Khurshid Iqbal Andrabi
This paper identifies mTORC2 as the physiological kinase responsible for hydrophobic motif phosphorylation of S6K1, demonstrating its activation after auto-inhibition by mTORC1.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · Feb 27, 2023Peer-reviewedMolecular Biology