Multi-omics co-localization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus
Marcus M. Soliai, Atsushi Kato, Catherine T. Stanhope, James E. Norton, Katherine A. Naughton, Aiko I. Klinger, Robert C. Kern, Bruce K. Tan, Robert P. Schleimer, Dan L. Nicolae, Jayant Marian Pinto, Carole Ober
The paper identifies context-specific genetic mechanisms at asthma risk loci by integrating multi-omics data with GWAS results in airway epithelial cells exposed to rhinovirus.
bioRxiv · Jun 2, 2020 · PreprintGenomics