Acute ketamine treatment produces long-term anxiolytic effects despite increasing oxidative stress in female Wistar Kyoto rats
Alena Lemeshova, Feysal Abdirahaman, Haney Haidari, Cherish Zhao, Aiman Limbada, Jennifer A. Honeycutt
This study examines the long-term anxiolytic effects of acute ketamine in female WKY rats, finding dose- and time-dependent behavioral changes alongside increased oxidative stress.
bioRxiv · Jul 1, 2026 · PreprintNeuroscience