Interplay of TGFb superfamily members governs optic fissure closure
Stephan Heermann, Priska Eckert, Juan L. Mateo, Eleni Roussa, Belal Rahhal, Aimee Zuniga, Kerstin Krieglstein, Jochim Wittbrodt
This study identifies TGFb signaling's role in optic fissure closure through ECM remodeling, regulated by BMP antagonists in zebrafish and supported by TGFb KO mouse coloboma phenotype.
bioRxiv · Oct 24, 2014 · PreprintDevelopmental Biology