Improved prediction of stabilizing mutations in proteins by incorporation of mutational effects on ligand binding
Srivarshini Ganesan, Nidhi Mittal, Akash Bhat, Rachana S. Adiga, Ananthakrishnan Ganesan, Deepesh Nagarajan, Raghavan Varadarajan
The paper improves stabilizing mutation prediction by combining computational methods with experimental data, achieving higher precision and thermal stability increases.
Proteins Structure Function and Bioinformatics · Aug 21, 2024Peer-reviewedBiophysics