Gut Stem Cell Secretome Therapy Promotes Durable Neuroprotection and Functional Recovery After Stroke
Kathiresh K Mani, Ann M Alex, Kaylin Pickle, Zara Akbari, Akruti Obhrai, Asmitha Senthil Kavithil, Netra Ashokraj, Srihari Ravindra Jadhav, Emily Stone, Nahla Adlouni, Gowtham Saksham, Kate Miller, Saarah Malik, Farida Sohrabji
This study shows that intestinal epithelial stem cell secretome improves gut repair and cognitive outcomes after stroke in male rats but not in female rats, highlighting the need for sex-specific therapies.
bioRxiv · Nov 4, 2026 · PreprintNeuroscience