Multivalency in endocytic accessory proteins orchestrates membrane shape transitions
Honey Priya James, Akshatha Manjunatha, Olivia Bullock, Tobias Baumgart
This study shows that multivalent SH3/PRM interactions between endophilin and lamellipodin regulate membrane curvature by suppressing tubulation through phase separation.
bioRxiv · Oct 27, 2026 · PreprintBiophysics